In the LDH-catalyzed reaction, lactate is converted to which product?

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Study for the Ciulla Clinical Chemistry Test. Enhance your knowledge with flashcards and multiple-choice questions. Prepare for the exam with comprehensive study materials and detailed explanations for each question.

Multiple Choice

In the LDH-catalyzed reaction, lactate is converted to which product?

Explanation:
LDH catalyzes the reversible interconversion of lactate and pyruvate, using NAD+/NADH as cofactors. In the direction from lactate to pyruvate, lactate is oxidized to pyruvate while NAD+ is reduced to NADH. That makes pyruvate the product in this direction. Acetyl-CoA would come from pyruvate via pyruvate dehydrogenase, and oxaloacetate is formed in other metabolic steps; lactate itself is the starting substrate here, not the product.

LDH catalyzes the reversible interconversion of lactate and pyruvate, using NAD+/NADH as cofactors. In the direction from lactate to pyruvate, lactate is oxidized to pyruvate while NAD+ is reduced to NADH. That makes pyruvate the product in this direction. Acetyl-CoA would come from pyruvate via pyruvate dehydrogenase, and oxaloacetate is formed in other metabolic steps; lactate itself is the starting substrate here, not the product.

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