Primary aldosteronism results from a tumor of the adrenal cortex. How would the extracellular fluid be affected?

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Study for the Ciulla Clinical Chemistry Test. Enhance your knowledge with flashcards and multiple-choice questions. Prepare for the exam with comprehensive study materials and detailed explanations for each question.

Multiple Choice

Primary aldosteronism results from a tumor of the adrenal cortex. How would the extracellular fluid be affected?

Explanation:
Excess aldosterone from an adrenal cortical tumor drives sodium reabsorption in the kidney and increases potassium excretion. Water follows sodium, so the extracellular fluid volume expands. The combined effect is more sodium in the extracellular space and less potassium due to the enhanced renal loss. So the extracellular fluid would have increased sodium and decreased potassium.

Excess aldosterone from an adrenal cortical tumor drives sodium reabsorption in the kidney and increases potassium excretion. Water follows sodium, so the extracellular fluid volume expands. The combined effect is more sodium in the extracellular space and less potassium due to the enhanced renal loss. So the extracellular fluid would have increased sodium and decreased potassium.

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