The Hollander insulin test is used to confirm vagotomy.

The Hollander insulin test is used to confirm vagotomy.

• A. Hyperglycemia
• B. Vagotomy
• C. Pancreatectomy
• D. Insulinoma

Answer: (B)

The key idea is how the vagus nerve controls insulin release from the pancreas. When glucose rises, the parasympathetic input from the vagus enhances insulin secretion. The Hollander insulin test checks this vagal-driven insulin response by giving a glucose challenge and measuring the resulting insulin rise. If vagal innervation has been cut by vagotomy, the insulin response is blunted or delayed, confirming that the vagus nerves have been successfully interrupted. This is a way to verify vagotomy rather than diagnose hyperglycemia, pancreatic removal, or an insulin-producing tumor.

The key idea is how the vagus nerve controls insulin release from the pancreas. When glucose rises, the parasympathetic input from the vagus enhances insulin secretion. The Hollander insulin test checks this vagal-driven insulin response by giving a glucose challenge and measuring the resulting insulin rise. If vagal innervation has been cut by vagotomy, the insulin response is blunted or delayed, confirming that the vagus nerves have been successfully interrupted. This is a way to verify vagotomy rather than diagnose hyperglycemia, pancreatic removal, or an insulin-producing tumor.