Which enzyme would not be useful to quantify in assessing liver function?

Which enzyme would not be useful to quantify in assessing liver function?

• A. Alanine aminotransferase
• B. Creatine kinase
• C. Alkaline phosphatase
• D. Gamma-glutamyltransferase

Answer: (B)

Enzyme markers for liver injury come from liver cells or the biliary system, so they directly reflect liver function or biliary status. Creatine kinase, on the other hand, is a muscle enzyme that rises with muscle damage, strenuous exercise, or myocardial injury, not with liver injury. The other enzymes—alanine aminotransferase, alkaline phosphatase, and gamma-glutamyltransferase—are associated with the liver and biliary tract and therefore provide relevant information about liver function or biliary obstruction. So creatine kinase would not be useful to quantify when assessing liver function.

Enzyme markers for liver injury come from liver cells or the biliary system, so they directly reflect liver function or biliary status. Creatine kinase, on the other hand, is a muscle enzyme that rises with muscle damage, strenuous exercise, or myocardial injury, not with liver injury. The other enzymes—alanine aminotransferase, alkaline phosphatase, and gamma-glutamyltransferase—are associated with the liver and biliary tract and therefore provide relevant information about liver function or biliary obstruction. So creatine kinase would not be useful to quantify when assessing liver function.