Which metabolic complication is commonly associated with multiple myeloma?

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Study for the Ciulla Clinical Chemistry Test. Enhance your knowledge with flashcards and multiple-choice questions. Prepare for the exam with comprehensive study materials and detailed explanations for each question.

Multiple Choice

Which metabolic complication is commonly associated with multiple myeloma?

Explanation:
Multiple myeloma often causes bone destruction due to malignant plasma cells in the bone marrow. The tumor environment stimulates osteoclast activity and suppresses osteoblasts, leading to osteolytic lesions. As bone is broken down, calcium is released into the blood, causing hypercalcemia. This metabolic complication is a hallmark of the disease and helps explain symptoms like bone pain and fatigue. Hyperalbuminemia, hyponatremia, or hypoglycemia are not typical metabolic derangements associated with this condition.

Multiple myeloma often causes bone destruction due to malignant plasma cells in the bone marrow. The tumor environment stimulates osteoclast activity and suppresses osteoblasts, leading to osteolytic lesions. As bone is broken down, calcium is released into the blood, causing hypercalcemia. This metabolic complication is a hallmark of the disease and helps explain symptoms like bone pain and fatigue. Hyperalbuminemia, hyponatremia, or hypoglycemia are not typical metabolic derangements associated with this condition.

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