Which statement about carcinoembryonic antigen is not true?

Which statement about carcinoembryonic antigen is not true?

• A. Increased levels seen with malignancies of the lungs
• B. Quantified by using capillary electrophoresis
• C. Used to monitor treatment of colon cancer
• D. Glycoprotein in nature

Answer: (B)

Carcinoembryonic antigen is a glycoprotein that serves as a tumor marker. Its levels are often elevated in various cancers, including colorectal cancer and some lung cancers, and serial measurements help monitor treatment response and detect recurrence, especially in colon cancer. Quantification of CEA relies on immunoassays that use antibodies to specifically detect the antigen, such as ELISA or chemiluminescent immunoassays. Capillary electrophoresis, while a separation technique for certain analytes, is not a standard method used to quantify CEA in clinical practice. Therefore, stating that CEA is quantified by capillary electrophoresis is not true.

Carcinoembryonic antigen is a glycoprotein that serves as a tumor marker. Its levels are often elevated in various cancers, including colorectal cancer and some lung cancers, and serial measurements help monitor treatment response and detect recurrence, especially in colon cancer. Quantification of CEA relies on immunoassays that use antibodies to specifically detect the antigen, such as ELISA or chemiluminescent immunoassays. Capillary electrophoresis, while a separation technique for certain analytes, is not a standard method used to quantify CEA in clinical practice. Therefore, stating that CEA is quantified by capillary electrophoresis is not true.